Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. • Metaxalone is used, along with rest and physical therapy, to treat injuries and other painful muscular conditions. • Metaxalone may also be used for purposes other than those listed in this medication guide.

What To Know

Use caution when driving, operating machinery, or performing other hazardous activities. Metaxalone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking metaxalone.

What Is It

Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. • Metaxalone is used, along with rest and physical therapy, to treat injuries and other painful muscular conditions. • Metaxalone may also be used for purposes other than those listed in this medication guide.

How To Use

• Take metaxalone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of water. • Store metaxalone at room temperature away from moisture and heat.

Missed Dose

You should take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

Over Dose

Seek emergency medical attention. • Symptoms of a metaxalone overdose are unknown but might include low blood pressure (weakness, fainting, confusion), nausea, severe drowsiness, decreased breathing, and unconsciousness.

Side Effects

If you experience any of the following serious side effects, stop taking metaxalone and seek emergency medical attention: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or · yellow skin or eyes. • Other, less serious side effects may be more likely to occur. Continue to take metaxalone and talk to your doctor if you experience · drowsiness or dizziness; · headache, nervousness, or irritability; or · nausea, upset stomach, or vomiting. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Precautions

Use caution when driving, operating machinery, or performing other hazardous activities. Metaxalone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking metaxalone.

Drug Interactions

Many drugs can increase the effects of metaxalone, which can lead to heavy sedation. Before taking this medication, tell your doctor if you are taking any of the following medicines: · antihistamines such as brompheniramine (Dimetane, Bromfed, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), azatadine (Optimine), clemastine (Tavist), and many others; · narcotics (pain killers) such as meperidine (Demerol), morphine (MS Contin, MSIR, others), propoxyphene (Darvon, Darvocet), hydrocodone (Lorcet, Vicodin), oxycodone (Percocet, Percodan), fentanyl (Duragesic), and codeine (Fiorinal, Fioricet, Tylenol #3, others); · sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), and secobarbital (Seconal); · phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), and trifluoperazine (Stelazine); or · antidepressants such as doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft), phenelzine (Nardil), and tranylcypromine (Parnate). • Drugs other than those listed here may also interact with metaxalone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.